一、基本信息

孙意冉，理学博士，毕业于四川大学。长期从事于中医药防治脑病的药理机制研究。主持中国博士后科学基金面上项目、河南省青年科学基金以及成都医学院高层次人才启动基金，参与过多项国家自然科学基金面上项目及省重点项目。以第一作者和通讯作者身份发表SCI 9篇，累计影响因子65+，H指数为10，其中中科院一区top期刊6篇，单篇影响因子最高为13.1。担任“TMR Pharmacology Discovery”期刊编委，“Traditional Medicine Research, Aging Communications, Food and Health”期刊青年编委，“Journal of Ethnopharmacology, Phytomedicine, APSB, Cellular & Molecular Biology Letters”等杂志特约审稿人。

二、主持科学研究项目

1.中国博士后科学基金会，面上项目，国家级，基于Ca2+/Calmodulin/GSK3β通路的开心散抑制神经元铁死亡抗AD机制研究，8万，2022M711080, 2023-01至2024-12，在研，主持；

2. 河南省自然科学基金，青年项目，省级，5万，232300421310，2023-01至2024-07，结项，主持；

3.河南中医药大学高层次人才引进专项经费A类，河南中医药大学，100万，结题，主持。

三、主持教学研究项目

无

四、主要讲授课程

1. 硕士研究生：无

2. 本科生课程：药理学

五、主要代表性成果

[1]Sun Y^#, Yan C^#, He L^#, Xiang S, Wang P, Li Z, Chen Y, Zhao J, Yuan Y, Wang W, Zhang X, Su P, Su Y, Ma J, Xu J, Peng Q^*, Ma H^*, Xie Z^*, Zhang Z^*. Inhibition of ferroptosis through regulating neuronal calcium homeostasis: An emerging therapeutic target for Alzheimer's disease.Ageing Res Rev. 2023, 87:101899.（IF=13.1, JCR前10%，中科院一区top期刊）

[2] Yang S^*,Sun Y^*,Yan C. Recent advances in the use of extracellular vesicles from adipose-derived stem cells for regenerative medical therapeutics. J Nanobiotechnology. 2024, 22(1):316.(第一通讯, IF=10.4, JCR前10%，中科院一区top期刊)

[3] Yan C^#, Yang S^#, Shao S^#, Zu R^#, Lu H, Chen Y, Zhou Y, Ying X, Xiang S, Zhang P, Li Z, Yuan Y, Zhang Z, Wang P, Xie Z^*, Wang W^*, Ma H^*,Sun Y^*. Exploring the anti-ferroptosis mechanism of Kai-Xin-San against Alzheimer's disease through integrating network pharmacology, bioinformatics, and experimental validation strategy in vivo and in vitro.J Ethnopharmacol. 2024, 326:117915.（主通讯，中科院一区top期刊）

[4]Sun Y^#, He L^#, Wang W^#, Wang T^#, Hua W, Li T, Wang L, Gao T, Chen F, Tang L^*. Polyphenols fromPenthorum chinensePursh. Attenuates high glucose-induced vascular inflammation through directly interacting with Keap1 protein.J Ethnopharmacol. 2021,268:113617.（中科院一区top期刊）

[5]Sun Y,He L, Wang W, Xie Z, Zhang X, Wang P, Wang L, Yan C, Liu Z, Zhao J, Cui Z, Wang Y, Tang L*, Zhang Z*. Activation of Atg7-dependent autophagy by a novel inhibitor of the Keap1-Nrf2 protein-protein interaction fromPenthorum chinensePursh. attenuates 6-hydroxydopamine-induced ferroptosis in zebrafish and dopaminergic neurons.Food Funct. 2022, 13(14):7885-7900.（中科院一区top期刊）

[6]Sun Y^#,Wang L^#, Lu Q^#, He L^#, Hua W, Zhang S, Wang T, Gu W, Li T, Tang L*. Phenols fragment ofVeronica ciliataFisch. ameliorate free radical-induced nonalcoholic fatty liver disease by mediating PI3K/Akt signaling pathway.J Ethnopharmacol. 2020, 253:112579.（中科院一区top期刊）

[7]Sun Y^#,He L^#, Wang T^#, Hua W^#, Qin H, Wang J, Wang L, Gu W, Li T, Li N, Liu X, Chen F, Tang L*. Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells.Mol Neurobiol. 2020, 57(11):4628-4641.（中科院二区，被引99次）

[8]Sun Y^#, Lu Q^#, He L, Shu Y, Zhang S, Tan S, Tang L^*. Active Fragment ofVeronica ciliataFisch. Attenuates t-BHP-Induced Oxidative Stress Injury in HepG2 Cells through Antioxidant and Antiapoptosis Activities.Oxid Med Cell Longev. 2017, 2017:4727151.（中科院二区）

[9] Gai G, Jie Z, Jing D, Shu L, Yan Shen, Chang L, Hui M, Yu F, Jiang X,Sun Y^*, Xiaowei Zhang^*, Zhenqiang Zhang^*, Zhishen Xie^*, Alisol B regulates AMPK/mTOR/SREBPs via directly targeting VDAC1 to alleviate hyperlipidemia,Phytomedicine, 2023, 155313.（共同通讯，JCR前10%，中科院一区top期刊）

[10] Yan CC,Sun YR^*. Targeting gut microbiota: an emerging therapeutic target for Parkinson's disease. Aging Commun. 2023;5(3):12.（第一通讯）

六、联系方式

E-mail：18202863885@163.com